Dr. Saha has co-authored 95 papers in highly reputed international journals and 150 conference papers/abstracts. Of these, 47 journal papers have been published since he joined the University of Iowa in 2006. His research works are widely internationally known and highly cited; current H-indices of his journal publications alone are 31 (per the web-of-knowledge) and 41 (per Google Scholar). He is also a co-inventor on six US patents.

Peer-Reviewed Journal Articles

(95) J Guo, C Wang, K-S Chan, D Jin, PK Saha, JP Sieren, RG Barr, MLK Han, E Kazerooni, CB Cooper, D Couper, JD Newell Jr, EA Hoffman, “Improved scanner surveillance in a multi-center longitudinal lung study by limiting test-object-based sources of variability. The SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS)”, Medical Physics, accepted under revision.

(94) KS Iyer, JD Newell-Jr, D Jin, MK Fuld, PK Saha, S Hansdottir, EA Hoffman, “Quantitative dual energy computed tomography supports a vascular etiology of smoking induced inflammatory lung disease” American Journal of Respiratory and Critical Care Medicine, in press.

(93) S Dudley-Javoroski, MA Petrie, CL McHenry, RE Amelon, PK Saha, RK Shields, “Bone architecture adaptations after spinal cord injury: impact of long-term vibration of a constrained lower limb”, Osteoporosis International, in press.

(92) PK Saha, S Basu, E Hoffman, “Multi-scale opening of conjoined fuzzy objects: theory and applications”, IEEE Transactions of Fuzzy Systems, in press.

(91) D Jin, KS Iyer, C Chen, EA Hoffman, PK Saha, “A Robust and Efficient Curve Skeletonization Algorithm for Tree-Like Objects Using Minimum Cost Paths”, Pattern Recognition Letters, in press.

(90) PK Saha, G Borgefors, G Sanniti di Baja, “A survey on skeletonization algorithms and their applications”, Pattern Recognition Letters, in press.

(89) A Hotca, CS Rajapakse, C Cheng, S Honig, K Egol, RR Regatte, PK Saha, G Chang, “In vivo measurement reproducibility of femoral neck microarchitectural parameters derived from 3T MR images”, Journal of Magnetic Resonance Imaging, 42(5), 1339-1345, 2015.

(88) PK Saha, R Strand, G Borgefors, “Digital topology and geometry in medical imaging: a survey”, IEEE Transactions on Medical Imaging, 34(9), 1940-1964, 2015 (invited paper).

(87) PK Saha, Y Liu, C Chen, D Jin, EM Letuchy, Z Xu, RE Amelon, TL Burns, JC Torner, SM Levy, CA Calarge, “Characterization of trabecular bone plate-rod micro-architecture using multi-row detector CT and the tensor scale: algorithms, validation, and applications to pilot human studies”, Medical Physics, 42(9), 5410-5425, 2015.

(86) C Li, D Jin, C Chen, EM Letuchy, KF Janz, TL Burns JC Torner, SM Levy, PK Saha, “Automated cortical bone segmentation for multirow-detector CT imaging with validation and application to human studies”, Medical Physics, 42(8), 4553-4565, 2015.

(85) N Das, R Sarkar, S Basu, PK Saha, M Kundu, M Nasipuri, “Handwritten Bangla character recognition using a soft computing paradigm embedded in two pass approach”, Pattern recognition, 48(6), 2054-2071, 2015.

(84) G Chang, D Xia, C Chen, G Madelin, SB Abramson, JS Babb, PK Saha, RR Regatte, “7T MRI detects deterioration in subchondral bone microarchitecture in subjects with mild knee osteoarthritis as compared with healthy controls”, Journal of Magnetic Resonance Imaging, 41(5), 1311-1317, 2015.

(83) SK Adhikari, JK Sing , DK Basu, M Nasipuri, PK Saha, “A nonparametric method for intensity inhomogeneity correction in MRI brain images by fusion of Gaussian surfaces”, Signal, Image and Video Processing, 9(8), 1945-1954, 2014.

(82) S Dudley-Javoroski, RE Amelon, Y Liu, PK Saha, RK Shields, “High bone density masks architectural deficiencies in an individual with spinal cord injury”, The Journal of Spinal Cord Medicine, 37(3), 349-354, 2014.

(81) KC Ciesielski, R Strand, F Malmberg, PK Saha, “Efficient algorithm for finding the exact minimum barrier distance”, Computer Vision and Image Understanding, 123, 53-64, 2014.

(80) Y Liu, D Jin, C Li, KF Janz, TL Burns JC Torner, SM Levy, PK Saha, “A robust algorithm for thickness computation at low resolution and its application to in vivo trabecular bone CT imaging”, IEEE Transactions on Biomedical Engineering, 61(7), 2057-2069, 2014.

(79) ML Raghavan, GV Sharda, J Huston III, J Mocco, AW Capuano, JC Torner,, PK Saha, I Meissner, RD Brown Jr., “Aneurysm shape reconstruction from biplane angiograms in the ISUIA collection”, Translational Stroke Research, 5(2), 252-259, 2014.

(78) R Strand, KC Ciesielski, F Malmberg, PK Saha, “The minimum barrier distance” Computer Vision
and Image Understanding, 117(4), 429-437, 2013.

(77) DM Vasilescu, Z Gao, PK Saha, L Yin, G Wang, B Haefeli-Bleuer, M Ochs, ER Weibel, EA Hoffman, “Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using multiscale microcomputed tomography” The Proceedings of the National Academy of Science (PNAS), 109(42), 17105-17110, 2012.

(76) Z Gao, RW Grout, C Holtze, EA Hoffman, PK Saha, “A new paradigm of interactive artery/vein separation in non-contrast pulmonary CT imaging using multi-scale topo-morphologic opening”, IEEE Transactions on Biomedical Engineering, 59(11), 3016-3027, 2012.

(75) S Dudley-Javoroski, PK Saha, G Liang, C Li, Z Gao, RK Shields, “High dose compressive loads attenuate bone mineral loss in humans with spinal cord injury”, Osteoporosis International, 23(9), 2335-2346, 2012.

(74) Z Xu, PK Saha, S Dasgupta, “Tensor scale: an analytic approach with efficient computation and applications”, Computer Vision and Image Understanding, 116(10), 1060-1075, 2012.

(73) Y Liu, G Liang, PK Saha, “A new multi-object image thresholding method based on correlation between object class uncertainty and intensity gradient”, Medical Physics, 39(1), 514-532, 2012.

(72) Y Xu, G Liang, G Hu, Y Yang, J Geng, PK Saha, “Quantification of coronary arterial stenoses in CTA using fuzzy distance transform”, Computerized Medical Imaging and Graphics, 36(1), 11-24, 2012.

(71) PK Saha, G Liang, JM Elkins, A Coimbra, LT Duong, DS Williams, M Sonka, “A new osteophyte segmentation algorithm using partial shape model and its applications to rabbit femur anterior cruciate ligament transection via micro-CT imaging” IEEE Transactions on Biomedical Engineering, 58(8), 2212-2227, 2011 (Featured on the journal’s cover)..

(70) Z Xu, M Sonka, PK Saha, “Improved tensor scale computation with application to medical image interpolation”, Computerized Medical Imaging and Graphics, 35(1), 64-80, 2011 (Featured on the journal’s cover).

(69) G. Chang, LG Wang, GY Liang, JS Babb, PK Saha, RR Regatte, “Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images”, MAGMA – European Society for Magnetic Resonance in Medicine & Biology, 24(3), 121-125, 2011.

(68) SCB Lam, MJ Wald, CS Rajapakse, Y Liu, PK Saha, FW Wehrli, “Performance of the MRI-based virtual bone biopsy in the distal radius: serial reproducibility and reliability of structural and mechanical parameters in women representative of osteoporosis study populations” Bone, 49(4), 895-903, 2011.

(67) G Chang, L Wang, G Liang, JS Babb, GC Wiggins, PK Saha, RR Regatte, “Quantitative assessment of trabecular bone micro-architecture of the wrist via 7 Tesla MRI: preliminary results”, MAGMA – European Society for Magnetic Resonance in Medicine & Biology, 24(4), 191-199, 2011.

(66) N Das, S Pramanik, R Sarkar, S Basu, PK Saha, “Recognition of isolated multi-oriented handwritten/printed characters using a novel convex-hull based alignment technique”, International Journal of Computer Applications, 1(23), 40-45, 2010.

(65) PK Saha, Y Xu, H Duan, A Heiner, G Liang, “Volumetric topological analysis: a novel approach for trabecular bone classification on the continuum between plates and rods”, IEEE Transactions on Medical Imaging, 29(11), 1821-1838, 2010.

(64) PK Saha, Z Gao, SK Alford, M Sonka, EA Hoffman, “Topo-morphologic separation of fused iso- intensity objects via multi-scale opening: separating arteries and veins in 3-D pulmonary CT”, IEEE Transactions on Medical Imaging, 29(3), 840-851, 2010.

(63) Y Zhuge, JK Udupa, J Liu, PK Saha, “Image background inhomogeneity correction in MRI via intensity standardization”, Computerized Medical Imaging and Graphics, 33(1), 7-16, 2009.

(62) J Liu, JK Udupa, PK Saha, D Odhner, BE Hirsch, S Siegler, S Simon, BA Winkelstein, “Rigid model-based 3D segmentation of the bones of joints in MR and CT images for motion analysis”, Medical Physics, 35(8), 3637-3649, 2008.

(61) FW Wehrli, GA Ladinsky, C. Jones, M Benito, J Magland, B. Vasilic, AM Popescu, B Zemel, AJ Cucchiara, AC Wright, HK Song, PK Saha, H Peachey, PJ Snyder, “In vivo magnetic resonance detects rapid remodeling changes in the topology of the trabecular bone network after menopause and the protective effect of estradiol”, Journal of Bone Mineral Research, 23(5), 730-740, 2008.

(60) G Chang, K S Pakin, ME Schweitzer, PK Saha, R Regatte, “Adaptations in trabecular bone microarchitecture in Olympic athletes determined by 7T MRI”, Journal of Magnetic Resonance Imaging, 27(5), 1089-1095, 2008.

(59) XS Liu, P Sajda, PK Saha, FW Wehrli, G Bevill, TM Keaveny, XE Guo, “Complete volumetric decomposition of individual trabecular plates and rods and its morphological correlations with anisotropic elastic moduli in human trabecular bone”, Journal of Bone Mineral Research, 23(2), 223-235, 2008.

(58) GA Ladinsky, B Vasilic, AM Popescu, M Wald, BS Zemel, PJ Snyder, L Loh, HK Song, PK Saha, AC Wright, FW Wehrli, “Trabecular structure quantified with the MRI-based virtual bone biopsy in postmenopausal women contributes to vertebral deformity burden independent of areal vertebral BMD”, Journal of Bone Mineral Research, 23(1), 64-74, 2008.

(57) PK Saha, B Das, FW Wehrli, “An object class-uncertainty induced adaptive force and its application to a new hybrid snake”, Pattern Recognition, 40(1), 2656-2671, 2007.

(56) KC Ciesielski, JK Udupa, PK Saha, Y Zhuge, “Iterative relative fuzzy connectedness for multiple objects with multiple seeds”, Computer Vision Image Understanding, 107(3), 160-182, 2007.

(55) TA Hopper, FW Wehrli, PK Saha, JB Andre, AC Wright, CP Sanchez, MB Leonard, “Quantitative microcomputed tomography assessment of intratrabecular, intertrabecular, and cortical bone architecture in a rat model of severe renal osteodystrophy”, Journal of Computer Assisted Tomography, 31(2), 320-328, 2007.

(54) MJ Wald, B Vasilic, PK Saha, FW Wehrli, “Spatial autocorrelation and mean intercept length analysis of trabecular bone anisotropy applied to in vivo magnetic resonance imaging”, Medical Physics, 34(3), 1110-1120, 2007.

(53) Y Kong, PK Saha, A Rosenfeld, “Strongly normal sets of tiles in n-dimensions”, Pattern Recognition, 40(2), 530-543, 2007.

(52) M Takahashi, PK Saha, FW Wehrli, “Skeletal effects of short-term exposure to dexamethasone and response to risedronate treatment studied in vivo in rabbits by magnetic resonance micro-imaging and spectroscopy”, Journal of Bone and Mineral Metabolism, 24(6), 467-475, 2006.

(51) FW Wehrli, HK Song, PK Saha, AC Wright, “Quantitative MRI for the assessment of bone structure and function”, NMR Biomedicine, 19(7), 731-764, 2006.

(50) XS Liu , P Sajda , PK Saha, FW Wehrli , XE Guo, “Quantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone”, Journal of Bone Mineral Research, 21(10), 1608-1617, 2006.

(49) CE Jones, RL Wolf, JA Detre, B Das, PK Saha, J Wang, Y Zhang, HK Song, AL Wright, ER Mohler, III, RM Fairman, EL Zager, OC Velazquez, MA Golden, HD Aronow, FW Wehrli, “Structural MRI of carotid artery atherosclerotic lesion burden and characterization of hemispheric cerebral blood flow before and after carotid endarterectomy”, NMR Biomedicine, 19(2), 198-208, 2006.

(48) Y Zhuge, JK Udupa, PK Saha, “Vectorial scale-based fuzzy connectedness image segmentation”, Computer Vision and Image Understanding, 101(3), 177-193, 2006.

(47) A Techawiboonwong, HK Song, J Magland, PK Saha, FW Wehrli, “Implications of pulse sequence in structural imaging of trabecular bone”, Journal of Magnetic Resonance Imaging, 22(5), 647-655, 2005.

(46) BR Gomberg, PK Saha, FW Wehrli, “Method for cortical bone structural analysis from magnetic resonance images”, Academic Radiology, 12(1), 1320-1332, 2005.

(45) PK Saha, “Tensor scale: a local morphometric parameter with applications to computer vision and image processing”, Computer Vision and Image Understanding, 99(3), 384-413, 2005.

(44) S Seigler, JK Udupa, SI Ringleb, CW Imahauser, BE Hirsch, D Odhner, PK Saha, E Okereke, N Roach, “Mechanics of the ankle and subtalar joints revealed through a 3D stress MRI technique”, Journal of Biomechanics, 38(3), 567-578, 2005.

(43) A Souza, JK Udupa, PK Saha, “Volume rendering in the presence of partial volume effects”, IEEE Transactions on Medical Imaging, 24(2), 223-235, 2005.

(42) N Sladoje, I Nyström, PK Saha, “Measurements of digitized objects with fuzzy borders in 2D and 3D”, Image and Vision Computing, (special issue on Discrete Geometry for Computer Imagery, eds I Nyström, GS di Baja, S Svensson), 23(2), 123-132, February, 2005.

(41) PK Saha, FW Wehrli, “A robust method measuring trabecular bone orientation anisotropy at in vivo resolution by using tensor scale”, Pattern Recognition, 37(9), 1935-1944, 2004.

(40) FW Wehrli, MB Leonard, PK Saha, BR Gomberg, “Quantitative high-resolution MRI reveals structural implications of renal osteodystrophy on trabecular and cortical bone”, Journal of Magnetic Resonance Imaging, 20(1), 83-89, 2004.

(39) BR Gomberg, FW Wehrli, B Vasilić, RH Weening, PK Saha, HK Song, AC Wright, “Reproducibility and error sources of μ-MRI-based trabecular bone structural parameters of the distal radius and tibia”, Bone, 35(1), 266-276, 2004.

(38) B Wang, PK Saha, JK Udupa, MA Ferrante, J Baumgardner, DA Roberts, RR Rizi, “3D airway segmentation via hyperpolarized 3He gas MRI using scale-based fuzzy connectedness”, Computerized Medical Imaging and Graphics, 28(1), 77-86, 2004.

(37) PK Saha, JK Udupa, AX Falcão, BE Hirsch, S Siegler, “Iso-shaping rigid bodies for estimating their motion from image sequences”, IEEE Transactions on Medical Imaging, 23(1), 63-72, 2004.

(36) PK Saha, FW Wehrli, “Measurement of trabecular bone thickness in the limited resolution regime of in vivo MRI by fuzzy distance transform”, IEEE Transactions on Medical Imaging, 23(1), 53-62, 2004.

(35) CL Chin, X Tang, LS Bouchard, PK Saha, WS Warren, FW Wehrli “Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI”, Journal of Magnetic Resonance, 165(2), 309-314, 2003.

(34) FW Wehrli, PK Saha, BR Gomberg, HK Song, “Noninvasive assessment of bone architecture by magnetic resonance micro-imaging-based virtual bone biopsy”, Proceedings of IEEE, Emerging Medical Imaging Technology, (invited paper), 91(10), 1520-1542, 2003.

(33) JK Udupa, PK Saha, “Fuzzy connectedness in image segmentation”, Proceedings of IEEE, Emerging Medical Imaging Technology, (invited paper), 91(10), 1649-1669, 2003.

(32) T Lei, JK Udupa, D Odhner, LG Nyúl, PK Saha, “3DVIEWNIX-AVS: A software package for the separate visualization of arteries and veins in CE-MRA images”, Computerized Medical Imaging and Graphics, 27(5), 351-362, 2003.

(31) LG Nyúl, JK Udupa, PK Saha, “Incorporating a measure of local scale in voxel-based 3-D image registration”, IEEE Transactions on Medical Imaging, 22(2), 228-237, 2003.

(30) BR Gomberg, PK Saha, FW Wehrli, “Topology-based orientation analysis of trabecular bone networks”, Medical Physics, 30(2), 158-168, 2003.

(29) RR Rizi, PK Saha, B Wang, M Aranda, D Lipson, J Baumgardner, DA Roberts, “Co-registration of acquired MR ventilation and perfusion images – validation in a porcine model”, Magnetic Resonance in Medicine, 49(1), 13-18, 2003.

(28) JK Udupa, PK Saha, RA Lotufo, “Relative fuzzy connectedness and object definition: theory, algorithms and applications in image segmentation”, IEEE Transactions on Pattern Analysis and Machine Intelligence, 24(11), 1485-1500, 2002.

(27) FW Wehrli, PK Saha, BR Gomberg, HK Song, PJ Snyder, M Benito, A Wright, R Weening, “Role of magnetic resonance for assessing structure and function of trabecular bone”, Topics in Magnetic Resonance Imaging, special issue edited by H Genant, 13(5), 335-355, 2002.

(26) JM Abrahams, PK Saha, RW Hurst, PD LeRoux, JK Udupa, “Three-dimensional bone-free rendering of the cerebral circulation using computed tomographic angiography and fuzzy connectedness”, Neurosurgery, 51(1), 264-269, 2002.

(25) PK Saha, FW Wehrli, BR Gomberg, “Fuzzy distance transform -- theory, algorithms, and applications”, Computer Vision and Image Understanding, 86(3), 171-190, 2002.

(24) T Lei, JK Udupa, PK Saha, D Odhner, R Baum, ST Tadikonda, EK Yucel, “3D MRA visualization and Artery-Vein Separation using blood-pool contrast agent MS-325”, Academic Radiology, 9(1), S127-S133, 2002.

(23) PK Saha, JK Udupa, “Scale-based image filtering preserving boundary sharpness and fine structures”, IEEE Transactions on Medical Imaging, 20(11), 1140-1155, 2001.

(22) PK Saha, JK Udupa, “Fuzzy connected object delineation: axiomatic path strength definition and the case of multiple seeds”, Computer Vision and Image Understanding, 83(3), 275-295, 2001.

(21) A. Rosenfeld, PK Saha, A Nakamura, “Interchangeable pairs of pixels in digital images”, Pattern Recognition, 34(9), 1853-1865, 2001.

(20) PK Saha, A Rosenfeld, “Local and global topology preservation in locally finite sets of tiles”, Information Sciences, 137(1), 303-311, 2001.

(19) PK Saha, JK Udupa, EF Conant, DP Chakraborty, D Sullivan, “Breast tissue density quantification via digitized mammograms”, IEEE Transactions on Medical Imaging, 20(8), 792-803, 2001.

(18) T Lei, JK Udupa, PK Saha, D Odhner, “Artery-vein separation via MRA -- an image processing approach”, IEEE Transactions on Medical Imaging, 20(8), 689-703, 2001.

(17) FW Wehrli, BR Gomberg, PK Saha, HK Song, SN Hwang, “Digital topological analysis of in vivo MR microimages of trabecular bone reveals structural implications of osteoporosis”, Journal of Bone and Mineral Research, 16(8), 1520-1531, 2001.

(16) PK Saha, JK Udupa, “Optimum threshold selection using class uncertainty and region homogeneity”, IEEE Transactions on Pattern Analysis and Machine Intelligence, 23(7), 689-706, 2001.

(15) PK Saha, JK Udupa, “Relative fuzzy connectedness among multiple objects: theory, algorithms and applications in image segmentation”, Computer Vision and Image Understanding, 82(1), 42-56, 2001.

(14) PK Saha, A Rosenfeld, “The digital topology of sets of convex voxels”, Graphical Models, 62(5), 343-352, 2000.

(13) BR Gomberg, PK Saha, HK Song, SN Hwang, FW Wehrli, “Topological analysis of trabecular bone MR images”, IEEE Transactions on Medical Imaging, 19(3), 166-174, 2000.

(12) PK Saha, JK Udupa, D Odhner, “Scale-based fuzzy connected image segmentation: theory, algorithms, and validation”, Computer Vision and Image Understanding, 77(2), 145-174, 2000.

(11) PK Saha, BR Gomberg, FW Wehrli, “Three-dimensional digital topological characterization of cancellous bone architecture”, International Journal of Imaging Systems and Technology, 11(1), 81- 90, 2000.

(10) PK Saha, A Rosenfeld, “Determining simplicity and computing topological change in strongly normal partial tilings of R2 or R3 ”, Pattern Recognition, 33(1), 105-118, 2000.

(9) PK Saha, D Dutta Majumder, A Rosenfeld, “Local topological parameters in a tetrahedral representation”, Graphical Models Image Processing, 60(6), 423-436, 1998.

(8) PK Saha, A Rosenfeld, “Strongly normal sets of convex polygons or polyhedra”, Pattern Recognition Letters, 19(12), 1119-1124, 1998.

(7) PK Saha and BB Chaudhuri and D Dutta Majumder, “A new shape preserving parallel thinning algorithm for 3D digital images”, Pattern Recognition, 30(12), 1939-1955, 1997.

(6) PK Saha, BB Chaudhuri, “3D Digital topology under binary transformation with applications”, Computer Vision and Image Understanding, 63(3), 418-429, 1996.

(5) PK Saha, D Dutta Majumder, “A topology and shape preserving thinning and segmentation method for 3D digital images”, Image Processing and Communications, 2(1), 3-34, 1996.

(4) PK Saha, BB Chaudhuri, “A new approach of computing Euler characteristic”, Pattern Recognition, 28(12), 1955-1963, 1995.

(3) PK Saha, BB Chaudhuri, “Detection of 3D simple points for topology preserving transformation with application to thinning”, IEEE Transactions on Pattern Analysis and Machine Intelligence, 16(10), 1028-1032, 1994.

(2) PK Saha, BB Chaudhuri, B Chanda, D Dutta Majumder, “Topology preservation in 3D digital space”, Pattern Recognition, 27(2), 295-300, 1994.

(1) PK Saha, B Chanda, D Dutta Majumder, “A single scan boundary removal thinning algorithm for 2-D binary objects”, Pattern Recognition Letters, 14(3), 173-179, 1993.